Carboxymethyl Cellulose Oxidation to Form Aldehyde Group

Oxidation of carboxymethyl cellulose (CMC) is a method of its modification, which allows to improve the functionality of this compound by increasing its reactivity. Presented work describes two methods of oxidation of carboxymethyl cellulose. The first is the conversion of CMC to its dialdehyde derivatives (DCMC) by sodium periodate. In the second method, hydrogen peroxide in the presence of iron tetrasulfophthalocyanine (FePcS) as catalyst was applied. Oxidation degree of CMC in different process parameters and time intervals was estimated using hydroxylamine hydrochloride. Modified CMC will be used in nanoparticles preparation in medical diagnostics.